Trzepacz PT, Hochstelter H, Wang S, Walker B, Saykin AJ. Avoiding spectrum bias caused by healthy controls. Diagnostic accuracy of the Montreal Cognitive Assessment (MoCA) for cognitive screening in old age psychiatry: determining cutoff scores in clinical practice. Validity of the Montreal Cognitive Assessment (MoCA) index scores: a comparison with the cognitive domain scores of the Seoul Neuropsychological Screening Battery (SNSB). Minorities and women are at greater risk for Alzheimer's disease. Cognitive performance on the Mini-Mental State Examination and the Montreal Cognitive Assessment across the healthy adult lifespan. Gluhm A, Goldstein J, Loc K, Colt A, Van Liew C, Corey-Bloom M. Orientation: You will be asked about the date, month, year, day, city, and place you are in.Delayed recall: You will be given five words and asked to repeat them back after five minutes.Abstraction: You will be asked what is in common between two different things (such as an apple and an orange, or a car and an airplane),.You will then be shown a series of capital letters and asked to pick out all of the "As." Language: You will first be asked to repeat back two different sentences verbatim.You will then be given a series of letters and asked to pick out the letter "A." Finally, you will be given several numbers and asked to subtract them from 100. Attention: You will first be given a series of numbers and asked to repeat them forward or backward.Naming: You will be shown pictures of three animals and asked what type of animal they are.Finally, you will be asked to draw a dial clock that reads 10 minutes past 11:00. Next, you will be given a drawing of a three-dimensional cube and asked to make a copy. Executive and visuospatial function: You will first be given a picture with numbered dots (1, 2, 3, 4, 5) and lettered dots (A, B, C, D, E) and asked to connect them sequentially, alternating numbers and letters.Also comparison of MOCA score between male and female of group A shows statistically significant difference with respect to MALE P=0.008 and FEMALE P=0.000.This study provides a strong evidence that Computer Based Cognitive Training showed added improvements in cognition function compared to traditional training. The comparison of difference of pre and post MOCA score between Group A and Group B shows p=0.002. Montreal cognitive assessment (MOCA) was taken as outcome measure. This randomized control trial includes 50 subjects, Group A received computer-based cognitive training (n=25) by using BrainHQ app and Group B received Tradition cognitive training (n=25) for 3 weeks. Computer-based cognitive training is a new tool used for cognitive rehabilitation. These changes are the cause of mild cognitive impairment in terms of decreased memory function, reduced speed and executive functions, personality and behavioral disturbances. Normal ageing cause alterations in the prefrontal cortex, medial temporal lobe system, hippocampus and cerebellum.
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